Respiratory and cardiac abnormalities in brain-stem ischaemia.

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Respiratory and cardiac abnormalities in brain-stem ischaemia.

Two patients are presented who had suffered episodes of ischaemia of the brain-stem, mainly affecting one side of the pons. In addition to the more usual neurological signs, these two patients had cardiac arrhythmia: one had a sinus arrhythmia, the other a wandering pacemaker. In both patients the hemidiaphragm on the side ipsilateral to the lesion was transiently elevated. The mechanisms respo...

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Intracellular calcium toxicity remains the central feature in the pathophysiology of ischaemic cell death in brain. Glutamate-gated channels have been thought to be the major sites of ischaemia-induced toxic calcium entry, but the failure of glutamate antagonists in clinical trials has suggested that glutamate-independent mechanisms of calcium entry during ischaemia must exist and may prove cen...

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ژورنال

عنوان ژورنال: Journal of Neurology, Neurosurgery & Psychiatry

سال: 1975

ISSN: 0022-3050

DOI: 10.1136/jnnp.38.2.187